What is the cause of chronic renal failure? What are the symptoms of chronic renal failure? First, the cause Chronic renal failure is extremely extensive, almost all the development of kidney disease can lead to deterioration of chronic renal failure. Acute renal failure without cure, a short period of time there is no death can also be a direct transition to chronic renal failure. The common reasons are described below: 1. Chronic glomerulonephritis progression to the late stage is the most common cause of chronic renal failure. 2. Interstitial nephritis (Interstitial Nephritis) is a group of mainly involving the renal interstitial and renal tubular disease, also known as tubulointerstitial nephropathy (Tubulo-Interstitia Nephropa-thy). Its complex causes, is a common clinical disease, accounting for Urinary system diseases of 25% to 33%, living in the second place of chronic renal failure. (1) infection: bacteria, viruses, mold, malaria parasite and other invasion of renal