Although the prognosis of IgA nephropathy is good, will not have a great impact on renal function, but after long-term study found that 10% of IgA nephropathy patients will show chronic progress, and gradually developed into end-stage renal failure. ...
Wang is less than 30 years old this year, is a company white-collar workers. Not long ago he had a cold, had thought that no serious, but found the hematuria, to the hospital to check down, diagnosed with IgA nephropathy.
In the past, had a good prognosis of IgA nephropathy, renal function will not have a great impact, but after long-term study found that 10% of IgA nephropathy patients will show chronic progress, and gradually developed into end-stage renal failure The
Therefore, we should attach great importance to the regular diagnosis and treatment of IgA nephropathy.
How early detection of IgA nephropathy
Young people have the following symptoms: urine changes, urine foam increased and difficult to spread, high blood pressure, eyelid and lower extremity edema, waist pain, unknown cause of renal insufficiency, especially the above symptoms occurred in the upper respiratory tract or gastrointestinal infection , The need for a high degree of suspected IgA nephropathy, should be promptly to the hospital Department of Nephrology specialist examination.
Transcutaneous nephrolithotomy biopsy for immunopathology is the only way to diagnose IgA nephropathy, and it is also important to guide the treatment and judge the prognosis. At present, B-guided use of skin and kidney puncture examination, easy operation, high success rate, trauma.
In recent years, the medical community has noticed that patients with IgA nephropathy have a higher proportion of abnormal urine tests in their family members, and the concept of familial IgA nephropathy is presented. IgA nephropathy in patients with family members should be regular urine examination, suspicious members should be a clear diagnosis of skin and kidney biopsy, with early detection, early treatment.
IgA nephropathy how to treat
Patients diagnosed with IgA nephropathy need to be treated by a kidney specialist specialist, depending on their different clinical manifestations and pathologic types.
(1) IgA nephropathy patients should pay attention to work and rest, to prevent a variety of infections, disable nephrotoxic drugs;
(2) IgA nephropathy in patients with protein intake should be controlled in the daily weight per kilogram of body weight 0.8 grams -1.0 grams, because the protein in the body of metabolites such as creatinine, uric acid and urea nitrogen and so on through the kidney excretion, increase the burden on the kidneys. Increased renal function can gradually increase the intake of protein, but to eggs, milk, fish and other high-quality protein-based. To eat more foods rich in vitamins and fruits;
(3) recurrent nausea hematuria IgA nephropathy, can be tonsillectomy;
(4) reduce proteinuria, IgA nephropathy patients should control the urine protein to 0.3 g / 24 hours or less;
(5) active control of high blood pressure, hypertensive patients should be reduced to 130 / 80mmHg blood pressure or 125 / 75mmHg below;
(6) part of the IgA nephropathy patients need glucocorticoid, cytotoxic drugs or immunosuppressive therapy;
(7) The study found that the main component of fish oil is a polyunsaturated fatty acids, with antioxidant effect, IgA nephropathy patients have some benefits.
IgA nephropathy how to follow
IgA nephropathy should be followed up regularly with blood pressure, urine, urine protein, renal function, and renal ultrasonography.
It is worth noting that the blood urea nitrogen and creatinine in the normal range, does not necessarily indicate normal renal function. Kidney has a strong reserve and compensatory function, only when the renal function decreased to normal below 30%, the blood urea nitrogen and creatinine value will exceed the normal range.
Can be used to understand the kidney function: 【(140 - age) × weight (kg) / (0.82 × serum creatinine), women and then multiplied by 0.85. Calculated value greater than 90, indicating normal renal function; between 90 and 60, indicating a slight decline in renal function; between 60 and 30, indicating a moderate decline in renal function; between 30 to 15, indicating a significant decline in renal function; For chronic renal failure, that is uremia.
Can IgA nephropathy be pregnant?
Usually most women with IgA nephropathy can tolerate pregnancy, but should be actively treated before pregnancy, control the condition. Pregnancy process, should be actively observed, followed by blood pressure, urine and 24 hours urine protein quantitative, renal function and so on. Female IgA nephropathy in patients with persistent severe hypertension, glomerular filtration rate of less than 60ml / function, skin and kidney biopsy biopsy showed severe renal vascular or interstitial lesions, should not be pregnant.
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