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IgA nephritis and differential diagnosis of four diseases

Four diseases and children with IgA nephropathy to make a differential diagnosis, so as not to confuse the disease, misdiagnosis, mistaken treatment, thus endangering the health of children, and even life safety. ...

In the differential diagnosis of IgA nephropathy in children, one thing is the need for special attention, namely: children with IgA nephropathy in the disease should be differentiated with the diagnosis of four diseases, the specific differential diagnosis is as follows:

1. Children with IgA nephropathy and purpura nephritis differential diagnosis:

Purpura nephritis, although also to hematuria as the main performance, but can be based on the history of allergic purpura to be identified. If necessary, can be diagnosed by renal biopsy.

2. Children with IgA nephropathy and lupus nephritis differential diagnosis:

Lupus nephritis manifested as microscopic or gross hematuria, often accompanied by multiple system involvement performance. By check blood complement C3, anti-nuclear antibodies, lupus cells and renal biopsy, generally difficult to identify.

3. Children with IgA nephropathy and hepatitis B virus-associated nephritis differential diagnosis:

Hepatitis B virus-associated glomerulonephritis can be expressed as hematuria, accompanied by a large number of urine protein, but the disease has liver enlargement and liver function abnormalities, HBsAg positive and / or HBeAg positive.

4. Children with IgA nephropathy and acute glomerulonephritis differential diagnosis:

Acute glomerulonephritis and more to hematuria as the main symptoms, may be associated with edema and high blood pressure, ESR often faster, total complement and C3 often decreased.


To sum up the four diseases and pediatric IgA nephropathy to make a differential diagnosis, so as not to confuse the disease, misdiagnosis, mistaken treatment, thus endangering the health of children, and even life safety.

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