IgA nephritis Common symptoms:
Small blood vessels fibrous necrosis, edema, fever, abdominal pain
First, the symptoms
The disease more common in older children and young people, men and women than 2: 1, often before the onset of upper respiratory tract infection incentives, but also by diarrhea, urinary tract infection induced reports. Clinical manifestations of diversity, from microscopic hematuria to nephrotic syndrome, can be the performance of the onset, the clinical phenotype can also change in the course of each other, but in the course of its clinical manifestations can change each other.
80% of children with IgA nephropathy with gross hematuria as the first symptom, North America and Europe, the incidence was higher than in Asia, often associated with upper respiratory tract infection (Berger disease); and upper respiratory tract infection interval is very short time (24 ~ 72h), even Hematuria occurs after a few hours.
And some children with hematuria and proteinuria, hematuria can be both for the onset of naring hematuria, but also for microscopic hematuria. Proteinuria is mostly mild to moderate.
Nephrotic syndrome for the performance of IgA nephropathy accounted for about 15% to 30%, "three high and one low" outstanding performance, often before the onset of respiratory tract infection is often rare.
There are also some cases of nephritis syndrome, in addition to hematuria, there are high blood pressure, renal insufficiency. Hypertension occurs in older age, adults accounted for 20%, children only 5%. Hypertension is an important indicator of the deterioration of IgA nephropathy, most associated with the rapid deterioration of renal function. Less than 5% of patients with IgA nephropathy showed progressive nephritis.
Second, the diagnosis
About 5-10% of IgA nephropathy in patients with acute renal failure onset, rapid nephritis syndrome is the leading cause of acute renal failure. Part of the IgA nephropathy in the first visit when the performance of chronic renal failure.
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