What should I do with a linear IgA bullous skin disease?

Linear IgA bullous skin disease common examination:
Common examination: immunopathological examination, serum immunoglobulin determination

One, check

Histopathology: lesions for the epidermal blisters, a large number of neutrophils along the basement membrane aggregation, often group in the dermal papilla, lymphocyte infiltration can be in the shallow dermis around the blood vessels. Some authors believe that the histopathology of the disease and herpes-like dermatitis is the difference between the less dermal papilla micro abscess and more diffuse basal membrane neutrophil infiltration, the vast majority of authors believe that histopathology IgA bullous dermatitis and herpes dermatitis are difficult to identify. Electron microscopy revealed that the blister was formed in the area under the transparent plate or dense plate. Direct immunofluorescence showed blister surrounding skin with homogeneous lamellar homogeneous linear IgA deposition, and some patients had IgM, IgG deposition. Indirect immunofluorescence can be found in patients with serum can detect anti-basement membrane low titer IgA antibodies, adult positive rate lower than children.

The above is for the linear IgA bullous dermatology should do what the relevant aspects of the investigation, the following look at the linear IgA bullous skin disease should be how to identify the diagnosis, linear IgA bullous skin disease easy to confuse the disease.

How does linear IgA bullous skin disease identify? :

One, identification

Should be identified with the following diseases:

1, the disease should be associated with bullous herpes class herpes and herpes-like dermatitis identification.

2, bullous epidermolysis, mostly in the early onset of the disease, often a positive family history, bullae often located in the vulnerable and friction parts. Among them, dysplasia may be blistering, leaving behind atrophic scar and pigment abnormalities, accompanied by nails, mucous membranes or dental dysplasia and hair loss.

3, acquired bullous epidermolysis of adult disease, vulnerable to trauma occurred blisters, scars, millet pimples, direct immunofluorescence examination basement membrane with IgG line deposition can be identified.